NFL Week 11 will have a clash of titans between the Tampa Bay Buccaneers and the Buffalo Bills. Their first encounter dates back to 1976, when Buffalo won 9-14, and since then, the Bucs have led the all-time series 8-5. Now, this will be the first time they have faced each other since October 2023, when Buffalo won 18-24. Here at BossAction we have our Buccaneers vs Bills prediction, along with everything you need to know.
How to Watch Buccaneers vs Bills
- Date: Sunday, November 16
- Time: 1:00 p.m. ET.
- Broadcast: FOX Sports
- Venue: Highmark Stadium
NFL Week 11 Preview: Buccaneers vs Bills Analysis
The Tampa Bay Buccaneers and Buffalo Bills are set for a game that could lead to playoff aspirations with two dynamic quarterbacks from the same draft class. Baker Mayfield and Josh Allen, selected first and seventh overall in the 2018 NFL Draft, have followed very different career paths; yet, both now lead competitive offenses capable of making big plays. Tampa Bay’s pass rush has been one of the most consistent in the league this season, racking up 15 sacks before the bye week, while Buffalo’s defense remains one of the toughest against the pass.
This matchup also features two coaching minds who rarely cross paths. Since taking over the Bills in 2017, Sean McDermott has faced the Buccaneers only three times, holding a 2-1 record. The game could come down to who handles adversity better because both teams are coming off tough losses and will be eager to reset their momentum. Maintaining focus, controlling turnovers, and protecting their quarterbacks will be crucial to staying in control throughout the entire game.
Allen vs. Mayfield. pic.twitter.com/w0cPCnaKtd
— Buffalo Bills (@BuffaloBills) November 13, 2025
Buccaneers Recent Form and Key Results
The Bucs started the season with solid victories over the Atlanta Falcons (20-23), the Houston Texans (19-20), and the New York Jets (29-27). It was not until Week 4 that their first loss arrived, courtesy of the current champions, the Philadelphia Eagles (31-25).
Then in Weeks 5 and 6, they rebounded with two consecutive victories over the Seattle Seahawks (35-38) and the San Francisco 49ers (30-19). Their last win was in Week 8 against the Saints (3-23), as they lost to the Detroit Lions (24-9) in Week 7 and the New England Patriots (28-23) in Week 10, respectively.
Buffalo Bills Season Recap
The Buffalo Bills have the same record as the Buccaneers (6-3) and a similar path of victories and defeats. They started rolling the season with four consecutive unbeaten games against the Baltimore Ravens (41-40), the New York Jets (30-10), the Miami Dolphins (31-21), and the New Orleans Saints (31-19). However, that streak was cut very fast with two back-to-back losses against the New England Patriots (23-20) and the Atlanta Falcons (24-14).
After the bye week, they returned to winning ways with victories against the Carolina Panthers (40-9) and the Kansas City Chiefs (28-21), only to fall short in a surprising loss against the Miami Dolphins (30-13) last week.
Buccaneers vs Bills Final Score and Forecast
It’s not often that the Buccaneers travel to Buffalo — in fact, this will be only their fourth regular-season visit in the past five decades. That rarity adds a bit of extra spice to a game already packed with offensive firepower. With both quarterbacks eager to make a statement and the Bucs showing more consistency on both ends of the ball, the edge goes to Tampa Bay. Our final BossAction prediction: Buccaneers 38-31 Bills.
